Back weight mgmt
Exercise and Blood Sugar
University Medical Center researchers have shown that long-term, intensive
exercise can significantly improve the body's ability to control blood sugar
levels, adding further evidence that exercise can forestall the development
of diabetes or cardiovascular disease in at-risk patients.
Furthermore, the researchers report, these beneficial effects of exercise
were maintained one month after the cessation of exercise. Previous studies
have shown that a single bout of exercise can improve glucose metabolism
immediately after exercise; however, the Duke researchers say, the
previously reported short-term effect disappears within 24 hours.
appears that there is also a long-term beneficial effect from regular
exercise, most likely due to the fact that a significant amount of fat is
lost," said exercise physiologist Cris Slentz, Ph.D., author of a study
appearing Feb. 15 in the journal Clinical Exercise Physiology. "Long-term
exercise leads to loss of fat in the gut (stomach) region, which is
especially beneficial since this fat is thought to be directly linked to
increased risk of diabetes and heart disease."
researchers wanted to see how exercise influenced the way the body
metabolized carbohydrates like glucose in people who had not yet developed
diabetes, but were at high risk. Previous studies were not only short-term,
but were conducted with elite or well-trained athletes who are not
representative of the general population. The current study is the first of
its kind using a "real-life" population of participants, the researchers
study, the Duke researchers put five overweight and sedentary people on an
intensive exercise regimen for nine months, followed by a one-month
"de-training" period. They measured blood levels of glucose and insulin
before the exercise training began, as well as one day, five days and 30
days after the training ended. To keep these results from being influenced
by what the patients consumed, the blood samples were taken after eight-hour
a hormone that is secreted by the pancreas after eating, is responsible for
the regulation of glucose levels in the blood; excessive amounts of insulin
can, over time, lead to the complications associated with diabetes and heart
sensitivity, or its ability to stimulate glucose metabolism, was higher
after nine months of exercise, and the fasting insulin levels were lower,"
Slentz said. "Just as importantly, 30 days after stopping exercise, insulin
sensitivity was still 24 percent higher than pre-exercise levels, indicating
that beneficial effects of exercise persisted."
study was supported by a grant from the National Institutes of Health (NIH).
results provide strong evidence that long-term exercise training can lead to
both short- and long-term improvements in carbohydrate metabolism," said
cardiologist Dr. William Kraus, senior member of the research team. "This
demonstrates the clinical significance of regular exercise in preventing the
development of insulin resistance and glucose intolerance in patients at
risk for diabetes and heart disease."
in the study did lose minimal amounts of weight (fat tissue weighs less than
muscle tissue), demonstrating that weight alone is not necessarily a good
marker for the risk of diabetes or heart disease.
surprisingly, the researchers added, the five patients also saw marked
improvements in blood cholesterol levels and exercise capacity.
exercise regimen was divided into two parts. The first three months
consisted of four exercise sessions a week, beginning with 15 minutes each
day and increasing to 60-70 minutes daily by the end of the three-month
period. For the remaining six months, patients maintained the same exercise
intensity and duration. The exercise program consisted of a combination of
stationary biking, treadmill walking and stair climbing.
these people, the amount of exercise was the equivalent of running 20 miles
per week, so we're talking about a large amount of exercise training," Kraus
said. "Our ultimate goal is to determine how much exercise does someone need
to achieve the maximum beneficial health effects. The prevailing advice
seems to be just do something, anything. I think we can do better than that
and come up with exercise guidelines or recommendations that are actually
based on concrete data. We still do not have good data on how often and at
what intensity is ideal for reducing the chances of developing diabetes or
answer these questions, Kraus is now enrolling patients in a trial
supported by a $4.3 million grant from the National Heart Lung and Blood
Institute. The current analysis of five patients was the pilot project that
allowed Kraus to start this much larger trial, which already has studied
more than 80 patients. He expects to have finished studying 160 patients by
N.C. - DukeMed News
WHY TAKE CHARGE OF SUGAR